First Baptist Church is a Baptist church located at 400 S. Broad Street in Burlington, Alamance County, North Carolina. It is affiliated with the Southern Baptist Convention. The church was built in 1922–1924, and is a two-story, brick Neoclassical Revival style church building with stone ornamentation. The front facade features an Ionic order hexastyle portico. The educational building was added in 1939 and a Sunday School and chapel wing in 1953. It was added to the National Register of Historic Places in 1984.