Duke of Villahermosa is a hereditary title in the peerage of Spain, accompanied by the dignity of Grandee and granted in 1476 by John II to Alfonso de Aragón, a half-brother of Ferdinand II. The ducal family's fortunes grew in the mid-15th century, after Pedrola became the Aragonese capital at the time when the Azlor de Aragón family estates and Villahermosa were controlled by Alfonso de Aragón y de Escobar, illegitimate son of King John II of Aragon. This noble family owned the Palace of Villahermosa in Madrid, a neo-classical building on the corner of Paseo del Prado and Calle de San Jerónimo, from the 18th century until the 20th century. Refurbished by Rafael Moneo in the late 1980s, the former ducal townhouse now houses Madrid's Thyssen-Bornemisza Museum.

List of dukes of Villahermosa