Debendra Pradhan (born 16 July 1941) is an Indian politician and a member of the Bharatiya Janata Party. He served as minister of state for surface transport and agriculture in the Second Vajpayee ministry. Pradhan was born on 16 July 1941 in undivided Dhenkanal District of Odisha and studied MBBS. He was elected to the 13th Lok Sabha from Deogarh constituency. He is also a member of the Rashtriya Swayamsevak Sangh. His son Dharmendra Pradhan is a Rajya Sabha MP from Madhya Pradesh and Union Minister of Education, Skill Development & Entrepreneurship in Narendra Modi Government.

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