Craig Creek (also known as Craig's Creek or Craigs Creek) is an 84 mi tributary of the James River in the U.S. state of Virginia. It flows through the Ridge-and-Valley Appalachians in western Virginia, passing 15 mi northwest of Roanoke. Craig Creek rises in Montgomery County, Virginia, 4 mi northwest of Blacksburg, in a valley between the parallel long ridges of Brush Mountain and Sinking Creek Mountain. It flows northeast into Craig County, passing the village of Webbs Mill. Turning north, the creek passes the town of New Castle at the eastern end of Sinking Creek Mountain, then continues generally northeast, though making continuous large incised meanders, into Botetourt County, where it joins the James River just upstream from the town of Eagle Rock.