The CONCACAF Giants Cup was an international soccer club competition held in 2001 to replace the CONCACAF Cup Winners Cup. The tournament was organized by CONCACAF for the 12 teams with the highest attendance in their respective national leagues. The winners and runners-up would qualify for the new CONCACAF Clubs Cup, which would serve as a qualification tournament for the FIFA Club World Championship. The Giants Cup was announced in November 2000 and planned to be one of the two primary annual club tournaments for CONCACAF alongside the more traditional Champions' Cup. The tournament's semifinals and final were originally scheduled to take place in late April in Los Angeles, but were later postponed to early August to accommodate conflicts with the teams' schedules. The prize money for the Giants Cup was set at $50,000 for the winner and $40,000 for the runners-up. Mexico's Club América won 2–0 in the final against D.C. United of the United States at the Los Angeles Memorial Coliseum, with 3,127 spectators in attendance. Both teams qualified for the CONCACAF Champions' Cup 2002, which replaced the Clubs Cup in October 2001.

First round

Arnett Gardens qualified for the quarterfinals. Saprissa qualified for the quarterfinals. Municipal qualified for the quarterfinals. Comunicaciones qualified for the quarterfinals.

Quarterfinals

D.C. United won 5–1 on aggregate. Comunicaciones won 4–2 on aggregate. América won 3–1 on aggregate. Saprissa won 3–1 on aggregate.

Semifinals

Final

Champion

Top goalscorers