Colle Santa Lucia (Ladin language: Col) is a comune (municipality) in the Province of Belluno in the Italian region of Veneto, located about 120 km north of Venice and about 40 km northwest of Belluno. As of 31 December 2004, it had a population of 408 and an area of 15.3 km2. The population speaks a Venetian dialect called Ladin Venetian that is heavily influenced by the Ladin language. Colle Santa Lucia borders the following municipalities: Alleghe, Cortina d'Ampezzo, Livinallongo del Col di Lana, Rocca Pietore, San Vito di Cadore, Selva di Cadore.

Demographic evolution