Colegio de San Lorenzo (CDSL) was a private Catholic college located in Barangay Bahay Toro, Quezon City and in Macabebe, Pampanga. It opened in 1988 in Quezon City and the branch in the founder's hometown of Macabebe opened in 1996. On August 15, 2022, Colegio de San Lorenzo announced it would be closing down and would cease operations by September 2022, citing financial instability and lack of financial viability due to the COVID-19 pandemic. The sudden announcement of its shutdown, on what would have been the school's first day of classes, brought negative responses from parents, students, and employees alike.

Gritty Griffins

SanLo's varsity team, the Griffins, is a member of the Universities, Colleges, and Schools Athletic Association (UCSAA) and the Universities and Colleges of Luzon Athletic Association (UCLAA). The senior basketball team won the UCSAA championship in four consecutive years, 2012 to 2015. They also won the Universities and Colleges Basketball League (UCBL) title in 2017. Jonjon Gabriel, a Griffin basketball player, went on to be selected in the first round of the 2017 PBA Draft. In 2018, their basketball team was disbanded.

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