Clyde B. Smith (February 4, 1906 – July 9, 1976) was an American football player, coach, and college athletics administrator. He served as the head football coach at La Crosse State Teachers College—now the University of Wisconsin–La Crosse (1938–1942, 1946–1947), Indiana University (1948–1951), and Arizona State University (1952–1954), compiling a career college football record of 52–56–4. From 1955 to 1971, he was the athletic director at Arizona State.

Head coaching record