Clinton AME Zion Church is a historic African Methodist Episcopal church located on Johnson Street between Marion and Richland Streets in Kershaw, Lancaster County, South Carolina. It was built in 1909, and is a one-story, T-shaped, Gothic Revival style frame structure covered with clapboard siding and has a brick pier foundation with concrete block infill. It was the first separate black church established in Kershaw in the early 20th century. It was added to the National Register of Historic Places in 1990.