Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 13 spans about 113 million base pairs (the building material of DNA) and represents between 3.5 and 4% of the total DNA in cells.

Genes

Number of genes

The following are some of the gene count estimates of human chromosome 13. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.

Gene list

The following is a partial list of genes on human chromosome 13. For complete list, see the link in the infobox on the right. • ARGLU1: encoding protein Arginine and glutamate-rich protein 1 • ATP7B: ATPase, Cu++ transporting, beta polypeptide (Wilson disease) • BRCA2: breast cancer 2, early onset • BRCA3 encoding protein Breast cancer 3 • C13orf42: encoding protein C13orf42 • CAB39L: encoding protein Calcium-binding protein 39-like • CARKD: Carbohydrate Kinase Domain Containing Protein (Unknown Function) • CCDC70: Coiled-coil domain-containing protein 70 • CHAMP1: Chromosome alignment-maintaining phosphoprotein 1 • CKAP2: Cytoskeleton-associated protein 2 • CLYBL: Citrate lyase beta like • CPB2-AS1: encoding protein Cpb2 antisense rna 1 • CRYL1: encoding protein Crystallin, lambda 1 • DLEU1: a long non-coding RNA • DLEU2: Deleted in lymphocytic leukemia 1 • DZIP1: DAZ interacting zinc finger protein 1 • EDNRB: endothelin receptor type B • ELF1: encoding protein E74-like factor 1 (ets domain transcription factor) • EPSTI1: encoding protein Epithelial stromal interaction 1 • ESD: S-formylglutathione hydrolase • FAM155A: encoding protein Family with sequence similarity 155, member A • FLT1: Fms related tyrosine kinase 1 (Vascular endothelial growth factor receptor 1) • GJB2: gap junction protein, beta 2, 26kDa (connexin 26) • GJB6: gap junction protein, beta 6 (connexin 30) • Glypican 5: encoding protein Glypican-5 • HTR2A: 5-HT2A receptor • INTS6: encoding protein Integrator complex subunit 6 • ITGBL1: encoding protein Integrin subunit beta like 1 • GPALPP1: encoding protein KIAA1704 • L1TD1P1: encoding protein LINE-1 type transposase domain containing 1 pseudogene 1 • LACC1: encoding protein Laccase (multicopper oxidoreductase) domain containing 1 • LHFP: encoding protein Lipoma HMGIC fusion partner • LINC00327: encoding protein Long intergenic non-protein coding RNA 327 • LINC00346: encoding protein Long intergenic non-protein coding RNA 346 • LINC00598: encoding protein Long intergenic non-protein coding rna 598 • LOC107984557 encoding protein Methylcytosine dioxygenase TET1-like • MBNL2: encoding protein Muscleblind-like protein 2 • MIPEP: encoding enzyme Mitochondrial intermediate peptidase • MIRH1: encoding protein Putative microRNA host gene 1 protein • MTRF1: • MTUS2: encoding protein Microtubule associated scaffold protein 2 • NDFIP2: encoding protein NEDD4 family-interacting protein 2 • NUPL1: encoding protein Nucleoporin p58/p45 • OLFM4: encoding protein Olfactomedin 4 • POMP: encoding proteasome maturation protein • PCCA: propionyl Coenzyme A carboxylase, alpha polypeptide • RB1: retinoblastoma 1 (including osteosarcoma) • RCBTB1: encoding protein RCC1 and BTB domain-containing protein 1 • RCBTB2: encoding protein RCC1 and BTB domain-containing protein 2 • RGCC: encoding protein Regulator of cell cycle RGCC • RNA28S1: encoding protein RNA, 28S ribosomal 1 • RNR1: encoding RNA, ribosomal 45S cluster 1 • SCEL: encoding protein Sciellin • SLC46A3: encoding protein Solute carrier family 46, member 3 • SLITRK1: encoding protein SLIT and NTRK-like protein 1 • SLITRK1: mutation in this gene causes some (although very few) cases of Tourette syndrome and trichotillomania • SLITRK5: encoding protein SLIT and NTRK-like protein 5 • SLITRK6: encoding protein SLIT and NTRK-like protein 6 • SOX21: Transcription factor SOX-21 is a protein that in humans is encoded by the SOX21; its disruption can lead to types of alopecia in mice. • SPRYD7: encoding protein SPRY domain-containing protein 7 • SUPT20H: SPT20 homolog • TDRD3: encoding protein Tudor domain-containing protein 3 • TM9SF2: encoding protein Transmembrane 9 superfamily member 2 • TPT1: Translationally controlled tumor protein (TCTP) • TSC22D1: encoding protein TSC22 domain family protein 1 • UBL3: encoding protein Ubiquitin-like protein 3 • WBP4: encoding protein WW domain-binding protein 4 • XPO4: encoding protein Exportin-4 • ZC3H13: encoding protein Zinc finger CCCH domain-containing protein 13 • ZMYM2: encoding protein Zinc finger MYM-type protein 2

Diseases and disorders

The following diseases and disorders are some of those related to genes on chromosome 13:

Chromosomal conditions

The following conditions are caused by changes in the structure or number of copies of chromosome 13:

Cytogenetic band