Casa de Piedra, also known as Residencia Amparo Roldán, in Aguadilla, Puerto Rico, is a Spanish Colonial-style home that was erected in 1875. It is the only surviving residence of its era in Aguadilla; most similar ones were damaged in the 1918 San Fermín earthquake and eventually demolished. It was listed on the National Register of Historic Places of Puerto Rico in 1986 and on the Puerto Rico Register of Historic Sites and Zones in 2000. It was built on stone foundations of an even older building that has been suggested to be the home of Ponce de Leon.