Boletus regineus, commonly known as the queen bolete, is an edible and highly regarded fungus of the genus Boletus that inhabits southwestern North America. It was considered a variant of the similarly edible B. edulis for many years until declared a unique species in 2008. Phylogenetic analysis has shown B. regineus as a member of a clade, or closely related group, with B. subcaerulescens, Gastroboletus subalpinus, B. pinophilus, B. fibrillosus, and B. rex-veris. The cap is 5–18 cm wide, convex then flat, brown with a whitish dusting when young. The stalk is 5–15 cm long, 3–6 cm wide, clavate then equal, and whitish tan.