Birrie River, a perennial river that is part of the Upper Darling catchment within the Murray–Darling basin, is located in the north-west slopes region of New South Wales, Australia. The river leaves the Bokhara River, about 7 km north–east of the village of Goodooga, and flows generally south and west, joined by three minor tributaries before reaching its confluence with the Culgoa River, north–east of Bourke and north–west of Brewarrina; descending 32 m over its 197 km course.