Amfecloral (INN), also known as amphecloral (USAN), is a central nervous system (CNS) stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the brand name Acutran, but is now no longer marketed. It was classified as an anorectic drug with little to no stimulant activity in a 1970 review. The British Pharmacopoeia Commission approved the name in 1970. The raw ingredients used in manufacturing it were dextroamphetamine and chloral hydrate.

Pharmacology

Amfecloral is metabolised to both d-(S)- and l-(R)-amphetamine and, most likely, also to chloral hydrate. Amphetamine is a stimulant, whereas chloral hydrate is a sedative/hypnotic drug. The extent of metabolism and in-vivo contribution of a chloral hydrate metabolism to its purported "little to no stimulant activity" is unknown.