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Alkanolamine
In organic chemistry, alkanolamines (amino alcohols) are organic compounds that contain both hydroxyl (\sOH) and amino (\sNH2, \sNHR, and \sNR2) functional groups on an alkane backbone. Most alkanolamines are colorless.
1-Aminoalcohols
1-Aminoalcohols are better known as hemiaminals. Methanolamine is the simplest member.
2-Aminoalcohols
2-Aminoalcohols are an important class of organic compounds that are often generated by the reaction of amines with epoxides: Simple alkanolamines are used as solvents, synthetic intermediates, and high-boiling bases. Hydrogenation or hydride reduction of amino acids gives the corresponding 2-aminoalcohols. Examples include prolinol (from proline), valinol (from valine), tyrosinol (from tyrosine). Key members: ethanolamine, dimethylethanolamine, N-methylethanolamine, Aminomethyl propanol. Two popular drugs, often called alkanolamine beta blockers, are members of this structural class: propranolol, pindolol. Isoetarine is yet another medicinally useful derivative of ethanolamine.
1,3-, 1,4-, and 1,5-amino alcohols
Natural products
Most proteins and peptides contain both alcohols and amino groups. Two amino acids are alkanolamines, formally speaking: serine and hydroxyproline.
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