Alice Bel Colle is a comune (municipality) in the Province of Alessandria in the Italian region Piedmont, located about 70 km southeast of Turin and about 25 km southwest of Alessandria. Alice Bel Colle borders the following municipalities: Acqui Terme, Cassine, Castel Rocchero, Castelletto Molina, Fontanile, Maranzana, Quaranti, and Ricaldone. The economy is mostly based on agriculture, including production of wine. It was a possession of the Marquisses of Montferrat until 1533.