Adolf Holtzmann (2 May 1810 in Karlsruhe – 3 July 1870 in Heidelberg) was a German professor and philologist. His name is associated with a Proto-Germanic sound law known as Holtzmann's Law. He studied theology at the universities of Halle and Berlin, where he was a student of Friedrich Schleiermacher. He later studied philology at the University of Munich, where his influences included Johann Andreas Schmeller. Holtzmann also attended classes in Paris given by Eugène Burnouf, and beginning in 1837, spent a number of years working as a tutor to members of Baden royalty. From 1852 he was a professor of German literature and Sanskrit at the University of Heidelberg, and a notable philologist of his day. Holtzmann was the father-in-law of Albrecht Kossel, German biochemist and 1910 Nobel laureate, by his marriage to Holtzmann's daughter, Luise, in 1886.

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