The 2010 Sarasota Open was a professional tennis tournament played on outdoor green clay courts. It was part of the 2010 ATP Challenger Tour. It took place in Longboat Key, Florida, United States between May 10 and May 16, 2010.

Singles main draw entrants

Seeds

Other entrants

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following players received the lucky loser spots: The following players received special exempt into the main draw:

Champions

Singles

🇯🇵 Kei Nishikori def. 🇦🇷 Brian Dabul, 2–6, 6–3, 6–4

Doubles

🇺🇸 Brian Battistone / 🇺🇸 Ryler DeHeart def. 🇩🇪 Gero Kretschmer / 🇩🇪 Alex Satschko, 5–7, 7–6(4), [10–8]