The 2010 SA Tennis Open was a tennis tournament played on hard courts indoors. It was the 2nd edition of the SA Tennis Open and was part of the ATP World Tour 250 series of the 2010 ATP World Tour. It took place in Johannesburg, South Africa from 1 February through 7 February 2010.

ATP entrants

Seeds

Other entrants

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw:

Finals

Singles

🇪🇸 Feliciano López defeated 🇫🇷 Stéphane Robert, 7–5, 6–1

Doubles

🇮🇳 Rohan Bopanna / 🇵🇰 Aisam-ul-Haq Qureshi defeated 🇸🇰 Karol Beck / 🇮🇱 Harel Levy 6–2, 3–6, [10–5]