The 2010 Nielsen Pro Tennis Championship was a professional tennis tournament played on outdoor hard courts. It was the 19th edition of the tournament which was part of the 2010 ATP Challenger Tour. It took place in Winnetka, Illinois, between 28 June and 4 July 2010.

ATP entrants

Seeds

Other entrants

The following players received wildcards into the singles main draw: The following players received entry as alternative: The following players received entry from the qualifying draw:

Champions

Singles

🇦🇷 Brian Dabul def. 🇺🇸 Tim Smyczek, 6–1, 1–6, 6–1

Doubles

🇺🇸 Ryler DeHeart / 🇨🇦 Pierre-Ludovic Duclos def. Rik de Voest / 🇮🇳 Somdev Devvarman, 7–6(4), 4–6, [10–8]