The 2010 MLS SuperDraft was the eleventh annual SuperDraft presented by Major League Soccer. It was held on January 14, 2010 in Philadelphia, Pennsylvania, during the 2010 NSCAA Convention. The 2010 SuperDraft consisted of four rounds with sixteen selections each, for a total of 64 players selected during the draft. The draft preceded the 2010 MLS season. Philadelphia served as host to the 2010 draft the same year the Philadelphia Union begin play in MLS. As an expansion team, Philadelphia received the rights to the first selection in each of the four rounds. As the champion from the 2009 MLS season, Real Salt Lake had the rights to the final selections in each round. As similar in other drafts, teams may trade these rights away to other teams for other rights such as players, special roster spots, or other rights of interest.

Player selection

Round one

Round one trades

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Round two

Round two trades

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Round three

Round three trades

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Round four

Round four trades

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Selections by affiliation

Selections by position

Trade note

2010 Supplemental Draft Trades

In December 2008 the league decided to cancel the Supplemental Draft, which had typically been held shortly after the annual SuperDraft. Prior to the cancellation a few trades were made involving 2010 Supplemental Draft picks. It is unknown what compensation, if any, clubs trading for 2010 Supplemental Draft picks received in lieu of the draft picks. Announced trades involving 2010 Supplemental Draft selections include: