The 2010 Family Circle Cup was a women's tennis event on the 2010 WTA Tour, which took place from April 12 to April 18. It was the 38th edition of the event and was hosted at the Family Circle Tennis Center, in Charleston, South Carolina, United States. It was the second and last event of the clay court season played on green clay. The total prize money offered at this tournament was US$700,000. Samantha Stosur won the singles title.

Entrants

Seeds

Other entrants

The following players received wildcards into the main draw: The following players received entry from the qualifying draw:

Notable withdrawals

The following players withdrew from the tournament for various reasons:

Finals

Singles

🇦🇺 Samantha Stosur defeated 🇷🇺 Vera Zvonareva, 6–0, 6–3

Doubles

🇺🇸 Liezel Huber / 🇷🇺 Nadia Petrova defeated 🇺🇸 Vania King / Michaëlla Krajicek, 6–3, 6–4