The 2010 Copa Libertadores de Fútbol Femenino was the second edition of the Copa Libertadores de Fútbol Femenino, CONMEBOL's premier annual international women's club tournament. The competition was played in São Paulo state, Brazil, from 2 to 17 October 2010. Santos were the defending champions and successfully defended their title, without conceding a single goal. All matches were played at Arena Barueri in Barueri. Gloria Villamayor and Noelia Cuevas won the top scorer award with 8 goals each.

Qualified teams

Venue

Round and draw dates

The draw for the competition took place on 13 September 2010.

First stage

The top two teams from each group advanced to the semifinals.

Group A

Match times are local time (UTC−3).

Group B

Match times are local time (UTC−3).

Final stages

Semifinals

Third place match

Final

Top scorer

The top of the goal scoring table.