The Arizona Diamondbacks' 2010 season, the franchise's 13th season in Major League Baseball, included the team's attempt to make the playoffs for the first time since 2007. On July 1, 2010, the Arizona Diamondbacks fired Manager A. J. Hinch following a 31–48 start to the 2010 season and promoted Kirk Gibson who had served as the bench coach of the team since the 2007 season. Along with the dismissal of Hinch came the firing of General Manager Josh Byrnes.

Edwin Jackson no-hitter

On June 25, 2010, in a game against the Tampa Bay Rays at Tropicana Field in St. Petersburg, Florida, Diamondbacks right-hander Edwin Jackson threw the second no-hitter in franchise history in a 1–0 victory in front of a crowd of 18,918. Jackson walked eight Rays batters and struck out six in a 149 pitch outing to complete the game, the only offense he received by his teammates came in the form of a solo home run by first baseman Adam LaRoche in the second inning.

Regular season

Season standings

National League West

National League Wild Card

Record vs. opponents

Game log

Roster

Player stats

Batting

Note: G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; AVG = Batting average; SB = Stolen bases

Pitching

Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts

Farm system