The 2010–11 Coppa Italia, also known as TIM Cup for sponsorship reasons, was the 64th edition of the domestic competition. As in the previous year, 78 clubs took part in the tournament. Internazionale were the cup holders and successfully retained the trophy. It was Inter Milan's last competitive title until winning the Serie A title in 2021.

Participating teams

Format and seeding

Teams entered the competition at various stages, as follows:

Matches

Elimination rounds

Section 1

Match details

First round

Second round

Third round

Fourth round

Section 2

Match details

First round

Second round

Third round

Fourth round

Section 3

Match details

First round

Second round

Third round

Fourth round

Section 4

Match details

First round

Second round

Third round

Fourth round

Section 5

Match details

First round

Second round

Third round

Fourth round

Section 6

Match details

First round

Second round

Third round

Fourth round

Section 7

Match details

First round

Second round

Third round

Fourth round

Section 8

Match details

First round

Second round

Third round

Fourth round

Final stage

Bracket

Round of 16

Quarter-finals

Semi-finals

First leg

Second leg

Internazionale won 2–1 on aggregate. Palermo won 4–3 on aggregate.

Final

Top goalscorers