Three-time defending champion Rafael Nadal successfully defended his title, defeating David Ferrer in the final 6–1, 4–6, 6–1, to win the singles title at the 2008 Barcelona Open. It was his record fourth title at the Barcelona Open.

Seeds

The top eight seeds receive a bye into the second round. • # 🇪🇸 Rafael Nadal (champion) • # 🇪🇸 David Ferrer (final) • # 🇦🇷 David Nalbandian (third round) • # 🇺🇸 James Blake (second round) • # 🇪🇸 Carlos Moyá (second round) • # 🇪🇸 Tommy Robredo (quarterfinals) • # 🇬🇧 Andy Murray (second round) • # Ivo Karlović (second round) • # 🇦🇷 Guillermo Cañas (third round) • # 🇪🇸 Nicolás Almagro (quarterfinals) • # 🇪🇸 Juan Carlos Ferrero (withdrew) • # 🇫🇮 Jarkko Nieminen (first round) • # 🇪🇸 Fernando Verdasco (first round) • # Stanislas Wawrinka (semifinals) • # 🇷🇺 Dmitry Tursunov (third round) • # 🇪🇸 Feliciano López (third round) • # 🇦🇷 Juan Ignacio Chela (quarterfinals)

Draw

Finals

Top half

Section 1

Section 2

Bottom half

Section 3

Section 4

Qualifying

Qualifying seeds

• # 🇪🇸 Daniel Gimeno Traver (qualified) • # 🇰🇿 Yuri Schukin (qualifying competition, lucky Loser) • # 🇪🇸 Rubén Ramírez Hidalgo (qualifying competition, lucky Loser) • # 🇷🇺 Andrey Golubev (qualifying competition) • # 🇧🇪 Christophe Rochus (first round) • # 🇷🇺 Mikhail Kukushkin (qualified) • # 🇺🇿 Denis Istomin (qualifying competition) • # 🇷🇺 Mikhail Ledovskikh (first round) • # 🇦🇹 Oliver Marach (qualifying competition) • # 🇪🇸 Marc López (qualified) • # 🇪🇸 Gabriel Trujillo Soler (qualified) • # 🇪🇸 Pere Riba (qualifying competition) • # 🇧🇾 Max Mirnyi (qualified) • # 🇪🇸 Miguel Ángel López Jaén (qualifying competition)

Qualifiers

• # 🇪🇸 Daniel Gimeno Traver • # 🇪🇸 Marc López • # 🇧🇾 Max Mirnyi • # 🇮🇹 Matteo Marrai • # 🇪🇸 José Antonio Sánchez de Luna • # 🇷🇺 Mikhail Kukushkin • # 🇪🇸 Gabriel Trujillo Soler

Lucky losers

• # 🇰🇿 Yuri Schukin • # 🇪🇸 Rubén Ramírez Hidalgo

Qualifying draw

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

Seventh qualifier