The 2006 Tampa Bay Devil Rays season was their ninth since the franchise was created. They finished last in the American League East, posting a league-worst record of 61–101. Their manager was Joe Maddon, who entered his first season with the Devil Rays. The Devil Rays' offense had the fewest runs (689), hits (1,395) and RBI (650) in Major League Baseball, as well as the joint-lowest batting average (.255) and lowest on-base percentage (.314).

Offseason

Regular season

Season standings

Record vs. opponents

Opening Day starters

Transactions

Roster

Player stats

Batting

Starters by position

''Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in''

Other batters

''Note: G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in''

Pitching

Starting pitchers

Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts

Other pitchers

Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts

Relief pitchers

Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts

Farm system

LEAGUE CHAMPIONS: Montgomery