The 2006–07 season was the 104th in the history of the Southern League, which is an English football competition featuring semi-professional and amateur clubs from the South West, South Central and Midlands of England and South Wales. This season was the first to feature the new Division One sections after reform of the Isthmian League structure.

Premier Division

The Premier Division consisted of 22 clubs, including 16 clubs from the previous season and six new clubs: Bath City won the league and were promoted to the Conference South along with play-off winners Maidenhead United, who returned to the Conference after relegation in 2006. Only Northwood were relegated this season, and the other clubs finished in the relegation zone were reprieved due to Farnborough Town and Scarborough folding, and Hayes merging with Yeading.

League table

Play-offs

Stadia and locations

Division One Midlands

After the end of the previous season, the regional divisions were restructured due to the reorganisation of the Isthmian League. Most of the previous season's Eastern Division clubs were transferred to the Isthmian League. Southern League Eastern and Western divisions were replaced by Division One Midlands and Division One South & West. Brackley Town won the division and were promoted to the Premier Division along with play-off winners Bromsgrove Rovers. Both clubs that finished in the relegation zone were reprieved, due to clubs folding or resigning from other leagues.

League formation

Division One Midlands consisted of 22 clubs, including 16 clubs from previous season Southern League divisions and six new clubs:

League table

Play-offs

Stadia and locations

Division One South & West

After the end of the previous season, the regional divisions were restructured due to the reorganisation of the Isthmian League. Most of the previous season's Eastern Division clubs were transferred to the Isthmian League. Southern League Eastern and Western divisions were replaced by Division One Midlands and Division One South & West. Bashley won the division and were promoted to the Premier Division along with play-off winners Swindon Supermarine. Hanwell Town and Beaconsfield SYCOB were relegated to the Spartan South Midlands League, while Lymington & New Milton resigned from the league before the next season started.

League formation

Division One South & West consisted of 22 clubs, including nine clubs from previous season Southern League divisions and 13 new clubs: At the end of the season Brook House changed name to AFC Hayes.

League table

Play-offs

Stadia and locations

League Cup

First round

Clubs playing in the Southern League Premier Division were exempt from the first round. All teams in the two divisions One entered the competition at this stage.

Second round

Cirencester Town and Northwood entered at this stage along with all the clubs who won their first round ties. All other Premier Division clubs were exempt.

Third round

All clubs who had been previously exempt entered at this stage of the competition along with the 12 teams who won their second round fixtures.

Fourth round

Quarter-finals

Semi-finals

Final