The 2005–06 season of the División de Honor de Futsal is the 17th season of top-tier futsal in Spain.

Regular season

League table

Playoffs

Championship playoffs

The Finals were broadcast in Spain on RTVE.

Championship playoffs matches

Quarter-finals

(8) MRA Gvtarra Navarra vs. (1) ElPozo Murcia Turística: ElPozo Murcia Turística wins the series 2-0 (7) PSG Móstoles vs. (2) Interviú Boomerang: Boomerang Interviú wins the series 2-0 (6) Playas de Castellón vs. (3) Polaris World Cartagena: Polaris World Cartagena wins the series 2-0 (5) A. Lobelle de Santiago vs. (4) Martorell: Martorell wins the series 2-1

Semifinals

(1) ElPozo Murcia Turística vs. (4) Martorell: ElPozo Murcia Turística wins the series 3-0 and qualifies to Finals (2) Interviú Boomerang vs. (3) Polaris World Cartagena: Polaris World Cartagena wins the series 3-1 and qualifies to Finals

Final

(1) ElPozo Murcia Turística vs. (3) Polaris World Cartagena: ElPozo Murcia Turística wins the Final 3-2 CHAMPION: : ElPozo Murcia Turística

Relegation playoff