The 2005–06 Danish Cup was the 52nd season of the Danish Cup. The first round was played on about 27 July 2005 and the final was played on 11 May 2006. This was the first time in the tournament's modern history that the final was not played on the afternoon of the Ascension Day. This was because of a new deadline for domestic competitions, enforced by FIFA. The cup winner, Randers FC, qualified for UEFA Cup qualification.

First round

In first round competed 48 teams from the "series" (2004 Denmark Series and lower) and 16 teams from 2004–05 Danish 2nd Divisions.

Second round

In second round competed 32 winning teams from first round and 8 teams from 2004–05 Danish 1st Division (no. 9 to 16).

Third round

In third round competed 20 winning teams from second round, 6 teams from 2004–05 Danish 1st Division (no. 3 to 8) and 2 teams from 2004–05 Danish Superliga (no. 11 and 12).

Fourth round

In fourth round competed 14 winning teams from third round, 2 teams from 2004–05 Danish 1st Division (no. 1 and 2) and 4 teams from 2004–05 Danish Superliga (no. 7 to 10).

Fifth round

In fifth round competed 10 winning teams from fourth round and 6 teams from 2004–05 Danish Superliga (no. 1 to 6).

Quarter-finals

Semi-finals

The semi finals were played on home and away basis. The draw took place on 6 March 2006. The legs were played on 20 and 27 April 2006.

Final