The 2001 Soul Train Music Awards were held on February 28, 2001, at the Shrine Auditorium in Los Angeles, California. The show was hosted by Queen Latifah, Mýa, and Shemar Moore.

Special awards

Quincy Jones Award for Career Achievement

Sammy Davis Jr. Award for "Entertainer of the Year" – Male

Sammy Davis Jr. Award for "Entertainer of the Year" – Female

Winners and nominees

Winners are in bold text.

R&B/Soul or Rap Album of the Year

Best R&B/Soul Album – Male

Best R&B/Soul Album – Female

Best R&B/Soul Album – Group, Band or Duo

Best R&B/Soul Single – Male

Best R&B/Soul Single – Female

Best R&B/Soul Single – Group, Band or Duo

The Michael Jackson Award for Best R&B/Soul or Rap Music Video

Best R&B/Soul or Rap New Artist

Best Gospel Album

Performers