The 2000 United States Senate election in Minnesota was held on November 7, 2000, to select a U.S. senator from the state of Minnesota. The race pitted incumbent Republican Senator Rod Grams against former Minnesota State Auditor Mark Dayton. Dayton won with 48.83% of the vote to Grams's 43.29%. Dayton declined to run for reelection in 2006 and ran successfully in 2010 and 2014 for governor of Minnesota. He was succeeded in the Senate by Amy Klobuchar, who has held the seat ever since. Upon Dayton's swearing in, Democrats held both of Minnesota's U.S. Senate seats for the first time since 1978. As of 2025, this is the last time that a man won the Class 1 Senate seat in Minnesota.

DFL primary

Results

Republican primary

Candidate

Results

General election

Candidates

Debates

Dayton and Grams had three debates, one on October 18, one on October 26, and one on November 3.

Results

Counties that flipped from Republican to Democratic