The 2000 CONCACAF Champions' Cup was the 36th edition of the annual international club football competition held in the CONCACAF region (North America, Central America and the Caribbean), the CONCACAF Champions' Cup. It determined that year's club champion of association football in the CONCACAF region. The tournament was played in Los Angeles, California, and won by the Los Angeles Galaxy over Olimpia in the final match. This was also the last win by an MLS team in CONCACAF's premier club competition, until Seattle Sounders FC won the 2022 CONCACAF Champions League.

Qualified teams

North American zone

Central American zone

Caribbean zone

Bracket

Quarterfinals

Semifinals

Third place match

Final

Champion