The 2000 Challenge Cup (officially known as the 2000 Silk Cut Challenge Cup for sponsorship reasons) is a rugby league football tournament which began its preliminary stages in December 1999 and ended with the final on 29 April 2000. The final was held on Saturday, 29 April 2000, at Murrayfield Stadium, Edinburgh, UK. The game was won by Bradford Bulls who defeated Leeds Rhinos 24–18.

First round

The first round was scheduled for the weekend of 4/5 December 1999 but due to cold weather leading to frozen pitches, a number of games were postponed. The last tie in the round was not played until 3 January 2000.

Second round

Third round

Fourth round

Fifth round

Quarter-finals

Semi-finals

Final