The 2000–01 QMJHL season was the 32nd season in the history of the Quebec Major Junior Hockey League. Sixteen teams played 72 games each in the schedule. The Shawinigan Cataractes finished first overall in the regular season, winning their second Jean Rougeau Trophy. Simon Gamache of the Val-d'Or Foreurs is the top scorer in the league, wins the regular season and playoff MVP awards, and three other individual awards at the season's end. Gamache helped Val-d'Or win their second President's Cup, defeating the Acadie-Bathurst Titan in the finals.

Final standings

Note: GP = Games played; W = Wins; L = Losses; T = Ties; OTL = Overtime loss; PTS = Points; GF = Goals for; GA = Goals against

Lebel Conference

Dilio Conference

Scoring leaders

Note: GP = Games played; G = Goals; A = Assists; Pts = Points; PIM = Penalty minutes

Playoffs

Simon Gamache was the leading scorer of the playoffs with 57 points (22 goals, 35 assists), setting the QMJHL playoff points record.

All-star teams

Trophies and awards