Defending champion Venus Williams defeated her sister Serena in the final, 6–1, 4–6, 6–4 to win the women's singles tennis title at the 1999 Miami Open.

Seeds

All seeds received a bye to the second round. • # Martina Hingis (semifinals) • # 🇺🇸 Lindsay Davenport (quarterfinals, withdrew) • # 🇺🇸 Monica Seles (fourth round) • # 🇨🇿 Jana Novotná (quarterfinals) • # 🇪🇸 Arantxa Sánchez Vicario (second round) • # 🇺🇸 Venus Williams (champion) • # 🇩🇪 Steffi Graf (semifinals) • # 🇫🇷 Mary Pierce (fourth round) • # Amanda Coetzer (quarterfinals) • # 🇫🇷 Nathalie Tauziat (third round) • # 🇫🇷 Sandrine Testud (second round) • # Patty Schnyder (fourth round) • # 🇷🇺 Anna Kournikova (fourth round) • # 🇫🇷 Amélie Mauresmo (third round) • # Irina Spîrlea (second round) • # 🇺🇸 Serena Williams (final) • # 🇧🇪 Dominique Van Roost (second round) • # 🇪🇸 Conchita Martínez (third round) • # 🇧🇾 Natasha Zvereva (fourth round) • # 🇦🇹 Barbara Schett (quarterfinals) • # 🇫🇷 Julie Halard-Decugis (third round) • # 🇮🇹 Silvia Farina (third round) • # 🇷🇺 Elena Likhovtseva (fourth round) • # 🇺🇸 Chanda Rubin (third round) • # 🇪🇸 Magüi Serna (third round) • # 🇸🇰 Henrieta Nagyová (third round) • # 🇩🇪 Anke Huber (fourth round) • # 🇪🇸 Virginia Ruano Pascual (third round) • # Cara Black (second round) • # Iva Majoli (second round) • # 🇫🇷 Nathalie Dechy (third round) • # 🇺🇸 Amy Frazier (third round)

Draw

Finals

Top half

Section 1

Section 2

Section 3

Section 4

Bottom half

Section 5

Section 6

Section 7

Section 8

Qualifying

Seeds

• # 🇸🇪 Åsa Carlsson (first round) • # Christína Papadáki (qualifying competition, lucky loser) • # Seda Noorlander (first round) • # Amanda Hopmans (first round) • # Kristie Boogert (first round) • # Emmanuelle Gagliardi (first round) • # 🇦🇷 Mariana Díaz Oliva (first round) • # 🇧🇬 Pavlina Stoyanova (first round) • # 🇮🇹 Adriana Serra Zanetti (qualifier) • # Janet Lee (qualifier) • # 🇩🇪 Marlene Weingärtner (qualifier) • # 🇦🇺 Alicia Molik (qualifier) • # 🇨🇿 Sandra Kleinová (qualifier) • # 🇺🇸 Jolene Watanabe (qualifying competition) • # 🇮🇹 Tathiana Garbin (qualifying competition) • # 🇺🇸 Alexandra Stevenson (first round)

Qualifiers

• # 🇮🇹 Adriana Serra Zanetti • # 🇩🇪 Marlene Weingärtner • # 🇨🇿 Sandra Kleinová • # 🇩🇪 Jana Kandarr • # 🇦🇺 Alicia Molik • # 🇺🇸 Meilen Tu • # Janet Lee • # Tina Pisnik

Lucky losers

Qualifying draw

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

Seventh qualifier

Eighth qualifier