The 1999–2000 network television schedule for the six major English language commercial broadcast networks in the United States covers primetime hours from September 1999 through August 2000. The schedule is followed by a list per network of returning series, new series, and series cancelled after the 1998–99 season. PBS is not included; member stations have local flexibility over most of their schedules and broadcast times for network shows may vary. Also not included are stations affiliated with Pax TV; although Pax carried a limited schedule of first-run programs, its schedule otherwise was composed mainly of syndicated reruns. New series highlighted in bold. All times are U.S. Eastern and Pacific Time (except for some live sports or events). Subtract for one hour for Central, Mountain, Alaska and Hawaii–Aleutian times. Each of the 30 highest-rated shows is listed with its rank and rating as determined by Nielsen Media Research.

Legend

Light blue indicates local programming. Gray indicates encore programming. Blue-gray indicates news programming. Light green indicates sporting events. Light purple indicates movies. Red indicates series being burned off and other regularly scheduled programs, including specials. Yellow indicates the top-10 most watched programs of the season. Cyan indicates the top-20 most watched programs of the season. Magenta indicates the top-30 most watched programs of the season.

Sunday

Monday

Tuesday

Note: On Fox, Ally aired as re-edited half-hour repeats of the original hour-long Ally McBeal series. On CBS, Falcone premieres at 9:00 p.m. on April 4, 2000. On UPN, Secret Agent Man was supposed to premiere at 9:00pm, but however due to the show not getting the "buzz" before the fall premiere, The Strip was premiered instead, and the show aired later on in a different night.

Wednesday

Note: On ABC, Clerks premiered at 9:30 p.m. on May 31, 2000.

Thursday

Note: On NBC, the sitcom Daddio premiered on March 23, 2000, at 8:30. On Fox, Family Guy only had two airings and one special Sunday airing, and then on March 7, 2000, the show was moved to Tuesdays. On The WB, Popular premiered Wednesday, September 29, 1999, at 9:00 pm. On Fox, Manchester Prep was supposed to air at 8–9, but it was cancelled at the last minute. On ABC, Then Came You was scheduled to air at 8:30 PM EST, but due to the show not getting the "buzz" before the fall premiere, Whose Line Is It Anyway? was aired at the last minute, and the show aired later on in a different night.

Friday

Saturday

By network

ABC

Not returning from 1998–99:

CBS

Not returning from 1998–99:

Fox

New series Not returning from 1998–99:

NBC

Not returning from 1998–99:

UPN

Not returning from 1998–99:

The WB

Not returning from 1998–99: Note: The * indicates that the program was introduced in midseason.

Renewals and cancellations

Renewals

ABC

CBS

Fox

NBC

UPN

The WB

Cancellations/series endings

ABC

CBS

Fox

NBC

UPN

The WB