The 1999–00 Cincinnati Bearcats men's basketball team represented University of Cincinnati as a member of Conference USA during the 1999–2000 NCAA Division I men's basketball season. The head coach was Bob Huggins, serving in his 11th year at the school. The team held the #1 ranking in the AP poll for 12 weeks during the season, but had their national championship hopes undermined when Naismith Player of the Year Kenyon Martin broke his leg during the Conference USA tournament. The Bearcats finished with a 29–4 record (16–0 C-USA).

Roster

Source

Schedule and results

!colspan=12 style=|Regular Season !colspan=12 style=|<span style=>Conference USA Tournament !colspan=12 style=|<span style=>NCAA Tournament

Rankings

^Coaches did not release a Week 1 poll.

• AP did not release post-NCAA Tournament rankings

Awards and honors

NBA draft selections