The 1988 CONCACAF Champions' Cup was the 24th. edition of the annual international club football competition held in the CONCACAF region (North America, Central America and the Caribbean), the CONCACAF Champions' Cup. It determined that year's club champion of association football in the CONCACAF region and was played from 11 March till 21 December 1988. The teams were split in 2 zones, North/Central America and Caribbean, (as North and Central America sections combined to qualify one team for the final), each one qualifying two teams to the final tournament. Hondurean club Olimpia beat Trinidarian side Defence Force 4–0 on aggregate to become champions, thus achieving their second CONCACAF trophy.

North/Central American Zone

Preliminary round

First round

North American Zone

Central American Zone

Played in Estadio Doroteo Guamuch Flores - Guatemala City, Guatemala

Central American Zone

Played in Estadio Nacional Chelato Uclés - Tegucigalpa, Honduras

Second round

Central American Zone

Played in Estadio Nacional Chelato Uclés - Tegucigalpa, Honduras

Third round

North/Central American Zone

Caribbean Zone

First round

Matches and results unknown: Zenith 🇸🇷 Robinhood Sion Hill Cardinals

Second round

Matches and results unknown: La Gauloise 🇯🇲 Seba United 🇬🇫 Sport Guyanais

Semi-finals

Final

First leg

Second leg

Champion