The St. Louis Cardinals 1980 season was the team's 99th season in St. Louis, Missouri, and the 89th season in the National League. The Cardinals went 74–88 during the season and finished fourth in the National League East, 17 games behind the eventual NL pennant and World Series champion Philadelphia Phillies. The Cardinals played the season under four different managers, Ken Boyer (fired June 8 between games of a double-header against the Expos in Montreal), Jack Krol (the second game of the double-header that same day), Whitey Herzog (June 9 until he was hired as the team's general manager in late August, succeeding John Claiborne, who was fired earlier in August) and Red Schoendienst (from late August to end of season). After the season, Herzog reclaimed the managerial job. This team set a record for the most Silver Slugger Award winners in one season: Keith Hernández (first base), Garry Templeton (shortstop), George Hendrick (outfielder), Ted Simmons (catcher), and Bob Forsch (pitcher). Hernández also won a Gold Glove.

Offseason

Regular season

Season standings

Record vs. opponents

Opening Day starters

Notable transactions

Roster

Player stats

Batting

Starters by position

''Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in''

Other batters

''Note: G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in''

Pitching

Starting pitchers

Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts

Other pitchers

Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts

Relief pitchers

Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts

Farm system

LEAGUE CHAMPIONS: Springfield, Arkansas