The 1980 Major League Baseball season was the Chicago White Sox' 80th in Major League Baseball, and the team's 81st season overall. They finished with a record of 70–90, good enough for fifth place in the American League West, 26 games behind the first-place Kansas City Royals. In 1979 and 1980, Bill Veeck made overtures to Denver interests. An agreement was reached to sell to Edward J. DeBartolo, Sr., who pledged to keep the club in Chicago. His offer was turned down by the owners. Veeck was forced to sell to a different investment group.

Offseason

Regular season

On October 4, 54-year-old Minnie Miñoso entered a game against the California Angels as a pinch hitter for third baseman Greg Pryor. In doing so, he became the first major leaguer since Nick Altrock to play in five different decades. He grounded out against Angels pitcher Frank Tanana.

Season standings

Record vs. opponents

Opening Day lineup

Notable transactions

Roster

Game log

Regular season

Bold = White Sox team member

Detailed records

Month-by-Month

Player stats

Batting

Note: G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; BB = Base on balls; SO = Strikeouts; AVG = Batting average; SB = Stolen bases

Pitching

Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; HR = Home runs allowed; BB = Walks allowed; K = Strikeouts

Farm system