The 1964 Houston Colt .45s season was the team's third season in Major League Baseball. It involved the Houston Colt .45s finishing in ninth place in the National League with a record of 66–96, 27 games behind the eventual World Series champion St. Louis Cardinals. It was their final season for the team at Colt Stadium before relocating their games to the Astrodome in 1965, along with the accompanying name change to the "Astros" for the '65 season.

Offseason

On April 8, just a few days before Opening Day, Colt .45s pitcher Jim Umbricht died of cancer. Umbricht had come back from cancer in 1963 to pitch in 35 games, but it returned during the offseason. His uniform number 32 would be retired by the Astros the following season.

Notable transactions

Regular season

On April 23, Houston pitcher Ken Johnson became the first pitcher in major league history to lose a complete game no-hitter in nine innings when he was beaten 1–0 by the Cincinnati Reds. Cincinnati's Pete Rose scored the only run of the game in the ninth inning, when he reached second base on an error and later scored.

Season standings

Record vs. opponents

Opening Day starters

Notable transactions

Roster

Player stats

Batting

Starters by position

''Note: Pos = Position; G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; Avg. = Batting average; HR = Home runs; RBI = Runs batted in; SB = Stolen bases'' Positional abbreviations: C = Catcher; 1B = First base; 2B = Second base; 3B = Third base; SS = Shortstop; LF = Left field; CF = Center field; RF = Right field

Other batters

''Note: G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; Avg. = Batting average; HR = Home runs; RBI = Runs batted in; SB = Stolen bases''

Pitching

Starting pitchers

Note: G = Games pitched; GS = Games started; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts

Other pitchers

Note: G = Games pitched; GS = Games started; IP = Innings pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts

Relief pitchers

Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts

Farm system

LEAGUE CHAMPIONS: San Antonio Statesville affiliation shared with Boston Red Sox